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Article

Systemic Senolysis in Naturally Aged Mice Using a FAST-PLV Gene Therapy Approach

2024-12-12

Abstract excerpt

<title>Abstract</title> <p> Approaches to eliminate senescent cells <italic>in vivo</italic> using transgenic mouse models have demonstrated significant improvements in lifespan, reduction in cancer incidence, and amelioration of age-related degeneration. These approaches require, however, that the organism be genetically engineered from the embryo and/or repeatedly dosed for the organism’s lifespan, making th...

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Literature Corpus work
6fafe819-5f59-5d83-a9cb-41e0a5a8ec29
DOI
10.21203/rs.3.rs-5575296/v1
Open publication

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Systemic Senolysis in Naturally Aged Mice Using a FAST-PLV Gene Therapy ApproachDOI 10.21203/rs.3.rs-5575296/v1
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