Article

A <i>qnr</i> -plasmid allows aminoglycosides to induce SOS in <i>Escherichia coli</i>

2021-04-30

Abstract excerpt

The plasmid-mediated quinolone resistance (PMQR) genes have been shown to promote high-level bacterial resistance to fluoroquinolone antibiotics, potentially leading to clinical treatment failures. In Escherichia coli , sub-inhibitory concentrations (sub-MIC) of the widely used fluoroquinolones are known to induce the SOS response. Interestingly, the expression of several PMQR qnr genes is controlled by the SOS...

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Literature Corpus work: 6f9c6804-bc6c-5be7-a9a8-9d7d94c4f9a9
DOI: 10.1101/2021.04.29.441945

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