Article

Novel phage-plasmid mediated mechanism of antibiotic heteroresistance in <i>Escherichia coli</i>

2026-08-19

Abstract excerpt

Antibiotic heteroresistance (HR) is a hard-to-detect phenotype where a subpopulation of resistant bacteria is present within a main susceptible population. Selection of this subpopulation during antibiotic treatment has been associated with treatment failure and increased mortality. HR is often unstable and caused by mechanisms that can transiently and reversibly increase the copy number of resistance genes, which...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0147b147-1dbe-5e2d-b7c4-10780a114f9b
DOI: 10.64898/2026.08.19.745698

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Novel phage-plasmid mediated mechanism of antibiotic heteroresistance in <i>Escherichia coli</i>DOI 10.64898/2026.08.19.745698Read

Distinct plasmid- and host-encoded mechanisms drive small plasmid copy number-mediated heteroresistance in <i>Escherichia coli</i>Semantic proximity Read

Phage-plasmids spread antibiotic resistance genes through infection and lysogenic conversionSemantic proximity Read

Heteroresistance in <i>Enterococcus faecalis</i> is prevalent for key antibiotics and mainly caused by mutationsSemantic proximity Read

Antibiotic heteroresistance generated by multi-copy plasmidsSemantic proximity Read

Collateral sensitivity associated with antibiotic resistance plasmidsSemantic proximity Read

Plasmidome AMR screening (PAMRS) workflow: a rapid screening workflow for phenotypic characterization of antibiotic resistance in plasmidomesSemantic proximity Read

Plasmids link antibiotic resistance genes and phage defense systems in <i>E. coli</i>Semantic proximity Read

Collateral Sensitivity Associated with Antibiotic Resistance PlasmidsSemantic proximity Read

Aminoglycoside heteroresistance in <i>Enterobacter cloacae</i> is driven by the cell envelope stress responseSemantic proximity Read

Molecular characteristics of phages located in Carbapenemase-Producing <i>Escherichia coli</i> clinical isolates: New Phage-Like PlasmidsSemantic proximity Read

Two novel trimethoprim resistance genes, dfra50 and dfra51 , identified in phage-plasmidsSemantic proximity Read

A newly-identified IncY plasmid from multi-drug resistant <i>Escherichia coli</i> isolated from dairy cattle feces in PolandSemantic proximity Read