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Plasmid-Mediated Quinolone Resistance: a Multifaceted Threat

1 Oct 2009

Abstract excerpt

Although plasmid-mediated quinolone resistance (PMQR) was thought not to exist before its discovery in 1998, the past decade has seen an explosion of research characterizing this phenomenon. The best-described form of PMQR is determined by the qnr group of genes. These genes, likely originating in aquatic organisms, code for pentapeptide repeat proteins. These proteins reduce susceptibility to quinolones by...

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PMID: 19822894
DOI: 10.1128/cmr.00016-09

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