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Emerging Plasmid-Mediated Quinolone Resistance Associated with the <i>qnr</i> Gene in <i>Klebsiella pneumoniae</i> Clinical Isolates in the United States

26 Mar 2004

Abstract excerpt

Although quinolone resistance commonly results from chromosomal mutation, recent studies indicate that such resistance can also be transferred on plasmids carrying the gene responsible, qnr. One hundred ten ciprofloxacin-resistant clinical isolates of Klebsiella pneumoniae and Escherichia coli from the United States were screened for the qnr gene by PCR and Southern hybridization of plasmid DNA. Conjugation...

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PMID: 15047532
DOI: 10.1128/aac.48.4.1295-1299.2004

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