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Article

The prognostic impact of germline 46/1 haplotype of Janus kinase 2 in cytogenetically normal acute myeloid leukemia.

Haematologica - 1 Nov 2011

Nahajevszky Sarolta, Andrikovics Hajnalka, Batai Arpad, Adam Emma, Bors Andras, Csomor Judit, Gopcsa Laszlo, Koszarska Magdalena, Kozma Andras, Lovas Nora, Lueff Sandor, Matrai Zoltan, Meggyesi Nora, Sinko Janos, Sipos Andrea, Varkonyi Andrea, Fekete Sandor, Tordai Attila, Masszi Tamas

Abstract excerpt

BACKGROUND: Prognostic risk stratification according to acquired or inherited genetic alterations has received increasing attention in acute myeloid leukemia in recent years. A germline Janus kinase 2 haplotype designated as the 46/1 haplotype has been reported to be associated with an inherited predisposition to myeloproliferative neoplasms, and also to acute myeloid leukemia with normal karyotype. The aim of...

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Identifiers

PMID: 21791467
DOI: 10.3324/haematol.2011.043885
PMCID: PMC3208678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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