Article

Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancer

2023-10-04

Abstract excerpt

Patient-derived organoid models of estrogen receptor-positive (ER+) breast cancer would provide a much-needed tool to understand drug resistance and disease progression better. However, the establishment and long-term maintenance of ER expression, function, and response in vitro remains a significant challenge. Here, we report the development of an ER+ breast tumor organoid medium (BTOM-ER) that conserves ER expre...

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Literature Corpus work: 6f45a405-f770-5e92-b877-251fb23858d7
DOI: 10.21203/rs.3.rs-3341539/v1

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