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Article

Identifying the effectiveness of 3D culture systems to recapitulate breast tumor tissue in situ.

Cellular oncology (Dordrecht, Netherlands) - 1 Apr 2024

Ludwik Katarzyna A, Greathouse Frances R, Han Samuel, Stauffer Kimberly, Brenin David R, Stricker Thomas P, Lannigan Deborah A

Abstract excerpt

PURPOSE: Breast cancer heterogeneity contributes to chemotherapy resistance and decreased patient survival. To improve patient outcomes it is essential to develop a technology that is able to rapidly select the most efficacious therapy that targets the diverse phenotypes present within the tumor. Breast cancer organoid technologies are proposed as an attractive approach for evaluating drug responses prior to...

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PMID: 37776423
DOI: 10.1007/s13402-023-00877-8
PMCID: PMC11090829

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