Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Steroid Hormone Receptor Positive Breast Cancer Patient-Derived Xenografts.

Hormones & cancer - 1 Feb 2017

Matthews Shawna B, Sartorius Carol A

Abstract excerpt

The vast majority of breast cancers are positive for estrogen receptor (ER) and depend on estrogens for growth. These tumors are treated with a variety of ER-targeted endocrine therapies, although eventual resistance remains a major clinical problem. Other steroid hormone receptors such as progesterone receptor (PR) and androgen receptor (AR) are emerging as additional prospective targets in breast cancer. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents, Hormonal
Share to Breast Neoplasms
Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Estrogen Receptor alpha

Share to Estrogens

Share to Receptors, Androgen

Share to Receptors, Progesterone

Share to Xenograft Model Antitumor Assays

Source

Open in PubMed Open full text

Identifiers

PMID: 27796944
DOI: 10.1007/s12672-016-0275-0
PMCID: PMC5291783

Genes

AR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Steroid Hormone Receptor Positive Breast Cancer Patient-Derived Xenografts.PMID 27796944Read ↗

New generation breast cancer cell lines developed from patient-derived xenograftsSemantic proximity Read ↗

Experimental models of endocrine responsive breast cancer: strengths, limitations, and useSemantic proximity Read ↗

Molecular, Cellular, and Technical Aspects of Breast Cancer Cell Lines as a Foundational Tool in Cancer ResearchSemantic proximity Read ↗

Current Update of Patient-Derived Xenograft Model for Translational Breast Cancer ResearchSemantic proximity Read ↗

Influence of Estrogen Treatment On ESR1+ and ESR1- Cells In ER+ Breast Cancer: Insights From Single-Cell Analysis of Patient-Derived Xenograft ModelsSemantic proximity Read ↗

Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signalingSemantic proximity Read ↗

An immune-humanized patient-derived xenograft model of estrogen-independent, hormone receptor positive metastatic breast cancer.Semantic proximity Read ↗

Integrated molecular and functional profiling identifies E0771 as a basal-like triple-negative breast cancer modelSemantic proximity Read ↗

A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models.Semantic proximity Read ↗

Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancerSemantic proximity Read ↗

Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancerSemantic proximity Read ↗

Molecular characterization of breast cancer cell lines by clinical immunohistochemical markersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.