Article

Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancer

2023-08-13

Abstract excerpt

Patient-derived organoid models of estrogen receptor-positive (ER+) breast cancer would provide a much-needed tool to better understand drug resistance and disease progression. However, the establishment and long-term maintenance of ER expression, function, and response in vitro remains a significant challenge. Here, we report the development of an ER+ breast tumor organoid medium (BTOM-ER) that conserves ER expre...

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Literature Corpus work: 56e70ffe-08f7-5da7-9230-9ffc8b5ab53b
DOI: 10.1101/2023.08.09.552657

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