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Article

Experimental models of endocrine responsive breast cancer: strengths, limitations, and use

1 Jan 2021

Abstract excerpt

Breast cancers characterized by expression of estrogen receptor-alpha; ESR1) represent approximately 70% of all new cases and comprise the largest molecular subtype of this disease. Despite this high prevalence, the number of adequate experimental models of ER+ breast cancer is relatively limited. Nonetheless, these models have proved very useful in advancing understanding of how cells respond to and resist...

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PMID: 34532657
DOI: 10.20517/cdr.2021.33

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