Article

Mechanical strengthening of cell-cell adhesion during mouse embryo compaction

2023-12-08

Abstract excerpt

Compaction is the first morphogenetic movement of the eutherian mammals and involves a developmentally regulated adhesion process. Previous studies investigated cellular and mechanical aspects of compaction. During mouse and human compaction, cells spread onto each other as a result of a contractility-mediated increase in surface tension pulling at the edges of their cell-cell contacts. However, how compaction may...

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Literature Corpus work: 6f427103-3f4b-5390-885c-4f29f70bcff9
DOI: 10.1101/2023.12.07.570568

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