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Article

Cell and Tissue Scale Forces Coregulate Fgfr2-Dependent Tetrads and Rosettes in the Mouse Embryo.

Biophysical journal - 23 May 2017

Wen Jun, Tao Hirotaka, Lau Kimberly, Liu Haijiao, Simmons Craig A, Sun Yu, Hopyan Sevan

Abstract excerpt

What motivates animal cells to intercalate is a longstanding question that is fundamental to morphogenesis. A basic mode of cell rearrangement involves dynamic multicellular structures called tetrads and rosettes. The contribution of cell-intrinsic and tissue-scale forces to the formation and resolution of these structures remains unclear, especially in vertebrates. Here, we show that Fgfr2 regulates both the...

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Identifiers

PMID: 28538157
DOI: 10.1016/j.bpj.2017.04.024
PMCID: PMC5444237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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