Article

Exploring Machine Learning Models to Uncover Pathways in ALS Pathogenesis Using Immunohistochemical Features

2025-12-27

Abstract excerpt

<h4>ABSTRACT</h4> Amyotrophic Lateral Sclerosis (ALS) is a degenerative disease of motor neurons that leads to muscle wasting, paralysis, and death, with an average life expectancy of 2–5 years. Approximately 10-15% of ALS cases are familial (fALS), typically linked to, but not always caused by identifiable inherited genetic mutations. The remaining 85–90% are considered sporadic ALS (sALS), which typically occur...

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Literature Corpus work: 6f31dd74-e25a-56bd-9046-3ccb93769559
DOI: 10.64898/2025.12.19.25342356

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