Article

Classification of ALS Molecular Subtypes: A Review of Machine Learning Applications and Their Clinical Value

2025-11-03

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by considerable heterogeneity in both its underlying biological mechanisms and clinical presentation. High-dimensional transcriptomic datasets offer an opportunity to characterise this variation at the molecular level; however, traditional statistical methods struggle with their scale and complexity. Machine learning approaches...

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Literature Corpus work: 62d8d5dc-7f8d-5b49-a96e-0338af20b440
DOI: 10.20944/preprints202510.2537.v1

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