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Article

Identification of potential pathways and biomarkers linked to progression in ALS.

Annals of clinical and translational neurology - 1 Feb 2023

Huber Roland G, Pandey Swapnil, Chhangani Deepak, Rincon-Limas Diego E, Staff Nathan P, Yeo Crystal Jing Jing

Abstract excerpt

OBJECTIVE: To identify potential diagnostic and prognostic biomarkers for clinical management and clinical trials in amyotrophic lateral sclerosis. METHODS: We analysed proteomics data of ALS patient-induced pluripotent stem cell-derived motor neurons available through the AnswerALS consortium. After stratifying patients using clinical ALSFRS-R and ALS-CBS scales, we identified differentially expressed proteins...

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Identifiers

PMID: 36533811
DOI: 10.1002/acn3.51697
PMCID: PMC9930436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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