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Inhibition of the type IV secretion system from antibiotic-resistant <i>Helicobacter pylori</i> clinical isolates supports the potential of Cagα as an anti-virulence target

2023-09-01

Abstract excerpt

Helicobacter pylori resistance to antibiotics is a growing problem and it increasingly leads to treatment failure. While the bacterium is present worldwide, the severity of the clinical outcomes is highly dependent on the geographical origin and genetic characteristics of the strains. One of the major virulence factors identified in H. pylori is the cag pathogenicity island ( cag PAI), which encodes a type IV s...

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Literature Corpus work
6f1a7e93-565d-50d5-8f30-dc614c3dbb21
DOI
10.1101/2023.09.01.555934
Open publication

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Inhibition of the type IV secretion system from antibiotic-resistant <i>Helicobacter pylori</i> clinical isolates supports the potential of Cagα as an anti-virulence targetDOI 10.1101/2023.09.01.555934
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