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Triglyceride-Glucose Indices, Genetic Susceptibility, and Incident Dementia Risk Across Early CKM Syndrome Stages: A UK Biobank Prospective Cohort Study

2026-08-12

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Insulin resistance, indicated by the triglyceride-glucose (TyG) index, is an emerging risk factor for cognitive decline. However, its interplay with genetic susceptibility in determining dementia risk remains unexplored, particularly during the early stages of Cardiovascular-Kidney-Metabolic (CKM) syndrome. We aimed to evaluate whether integrating genetic susc...

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Literature Corpus work: 6eeb3064-abb0-5c49-92bc-251c4617996b
DOI: 10.21203/rs.3.rs-10150947/v1

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