Article

Integrating the environmental and genetic architectures of mortality and aging

2023-03-14

Abstract excerpt

It has long been suggested that environmental exposures (i.e., the exposome) play a dominant role in shaping trajectories of human aging and premature mortality. Here we aimed to quantify the contribution of the exposome and genome to aging and mortality. We conducted an exposome-wide analysis in the UK Biobank (n=492,567) to systematically identify exposures associated with mortality while accounting for exposure...

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Literature Corpus work: 9c9055dd-93e5-5a3c-bcdc-71712293ad79
DOI: 10.1101/2023.03.10.23286340

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