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The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets

2019-08-08

Abstract excerpt

<h4>Background</h4> Praziquantel represents the frontline chemotherapy used to treat schistosomiasis, a neglected tropical disease (NTD) caused by infection with macro-parasitic blood fluke schistosomes. While this drug is safe, its inability to kill all schistosome lifecycle stages within the human host often requires repeat treatments. This limitation, amongst others, has led to the search for novel anti-schist...

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Literature Corpus work
6e8f2be3-37b8-52ce-8abd-b6ce6ecb20fa
DOI
10.1101/729814
Open publication

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The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targetsDOI 10.1101/729814
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