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Article

Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities

2020-11-13

Abstract excerpt

<h4>Background: </h4> Schistosomiasis, caused by infection with blood fluke schistosomes, is a neglected tropical disease of considerable importance in resource-poor communities throughout the developing world. In the absence of an immunoprophylactic vaccine and due to over-reliance on a single chemotherapy (praziquantel), schistosomiasis control is at risk should drug insensitive schistosomes develop. In this con...

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Literature Corpus work
f5ea69c5-491d-50ae-9e15-a9cb6fb44205
DOI
10.12688/wellcomeopenres.16069.2
Open publication

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Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activitiesDOI 10.12688/wellcomeopenres.16069.2
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