Article
Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents.
ACS infectious diseases - 10 Jan 2020
Saccoccia Fulvio, Brindisi Margherita, Gimmelli Roberto, Relitti Nicola, Guidi Alessandra, Saraswati A Prasanth, Cavella Caterina, Brogi Simone, Chemi Giulia, Butini Stefania, Papoff Giuliana, Senger Johanna, Herp Daniel, Jung Manfred, Campiani Giuseppe, Gemma Sandra, Ruberti Giovina
Abstract excerpt
Schistosomiasis (also known as bilharzia) is a neglected tropical disease caused by platyhelminths of the genus Schistosoma. The disease is endemic in tropical and subtropical areas of the world where water is infested by the intermediate parasite host, the snail. More than 800 million people live in endemic areas and more than 200 million are infected and require treatment. Praziquantel (PZQ) is the drug of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.