Article

Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes

2023-03-30

Abstract excerpt

<h4>Background: </h4> : Schistosoma mansoni , a parasitic worm species responsible for the neglected tropical disease schistosomiasis, undergoes strict developmental regulation of gene expression that is carefully controlled by both genetic and epigenetic processes. As inhibition of S. mansoni epigenetic machinery components impairs key transitions throughout the parasite’s digenetic lifecycle, a greater underst...

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Literature Corpus work: 7c122370-577d-5bcb-994f-c61e8da44970
DOI: 10.12688/wellcomeopenres.18826.1

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