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Dietary emulsifiers and host inflammation synergistically drive genomic evolution of Crohn’s disease-associated <i>E. coli</i> toward enhanced pathogenicity

2026-04-20

Abstract excerpt

<h4>Background and Aims</h4> The rising incidence of Crohn’s disease (CD) in Westernized countries has been linked to changes in diet and increased consumption of food additives, yet the mechanisms by which these factors fuel intestinal inflammation remain unclear. Adherent-invasive Escherichia coli (AIEC), a pathobiont involved in CD pathogenesis, lacks a clear genetic hallmark but exhibits intestinal colonizat...

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Literature Corpus work
6e636e3a-f40a-5d7b-88c7-d5347fb17027
DOI
10.64898/2026.04.20.719593
Open publication

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