Article

Pervasive bacterial and prophage hybridization during chronic gut inflammation

2026-05-27

Abstract excerpt

<h4>Summary</h4> Inflammatory bowel diseases (IBD) are modulated by microbiota composition, host genetics, and environmental factors 1 . Humans and other mammals are colonized by multiple strains of Escherichia coli , a species that expands in abundance in IBD patients 2 . The state of chronic inflammation characteristic of IBD is expected to intensify selective pressures on the gut microbial community, leadin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b3312576-b93b-583c-95a3-f24d371fe595
DOI: 10.64898/2026.05.27.728231

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pervasive bacterial and prophage hybridization during chronic gut inflammationDOI 10.64898/2026.05.27.728231Read

Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiotaSemantic proximity Read

A consortia of clinical E. coli strains with distinct in-vitro adherent/invasive properties establish their own co-colonization niche and shape the intestinal microbiota in inflammation-susceptible miceSemantic proximity Read

Evolution of <i>E. coli</i> in a mouse model of inflammatory bowel disease leads to a disease-specific bacterial genotype and trade-offs with clinical relevanceSemantic proximity Read

Evolution of E. coli in a mouse model of inflammatory bowel disease leads to a disease-specific bacterial genotype and trade-offs with clinical relevance.Semantic proximity Read

Gut inflammation can boost horizontal gene transfer between pathogenic and commensal <i>Enterobacteriaceae</i>Semantic proximity Read

Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiotaSemantic proximity Read

Dietary emulsifiers and host inflammation synergistically drive genomic evolution of Crohn’s disease-associated <i>E. coli</i> toward enhanced pathogenicitySemantic proximity Read

Discovering Broader Host Ranges and an IS-bound Prophage Class Through Long-Read MetagenomicsSemantic proximity Read

Targeted protein evolution in the gut microbiome by diversity-generating retroelementsSemantic proximity Read

Evolutionary change in the human gut microbiome: From a static to a dynamic viewSemantic proximity Read

Discovery of disease-adapted bacterial lineages in inflammatory bowel diseases.Semantic proximity Read

The enemy from within: a prophage of Roseburia intestinalis systematically turns lytic in the mouse gut, driving bacterial adaptation by CRISPR spacer acquisitionSemantic proximity Read