Article

Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4

2003-12-01

Abstract excerpt

Lipid A is the pro-inflammatory component of bacterial lipopolysaccharide, the major surface component of Gram-negative bacteria. Gram-negative bacteria alter the structure of lipid A in response to specific environmental conditions including those found upon colonization of a host. The opportunistic pathogen Pseudomonas aeruginosa synthesizes a unique hexa-acylated lipid A containing palmitate and aminoarabinose...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6e3886c4-bfe1-5ce4-9069-23fed7382f7a
DOI: 10.1177/09680519030090060201

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4DOI 10.1177/09680519030090060201Read

Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4.Semantic proximity Read

Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa.Semantic proximity Read

A divergent Pseudomonas aeruginosa palmitoyltransferase essential for cystic fibrosis-specific lipid A.Semantic proximity Read

Pseudomonas aeruginosa Exploits Lipid A and Muropeptides Modification as a Strategy to Lower Innate Immunity during Cystic Fibrosis Lung InfectionSemantic proximity Read

Structural Relationship of the Lipid A Acyl Groups to Activation of Murine Toll-Like Receptor 4 by Lipopolysaccharides from Pathogenic Strains of Burkholderia mallei, Acinetobacter baumannii, and Pseudomonas aeruginosaSemantic proximity Read

A <i>Pseudomonas aeruginosa</i> hepta-acylated lipid A variant associated with cystic fibrosis selectively activates human neutrophilsSemantic proximity Read

Role of CFTR, Pseudomonas aeruginosa and Toll-like receptors in cystic fibrosis lung inflammationSemantic proximity Read

Engineering low-endotoxin lipid A in a double auxotroph Pseudomonas aeruginosa to develop safer whole-cell vaccines.Semantic proximity Read

Distinct biological activity of lipopolysaccharides with different lipid A acylation status from mutant strains of Yersinia pestis and some members of genus Psychrobacter.Semantic proximity Read

Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepaciaSemantic proximity Read

Human TLR4 and noncanonical inflammasome differ in their ability to respond to distinct lipid A variantsSemantic proximity Read

Microbial Lipid A Remodeling Controls Cross-Presentation Efficiency and CD8 T Cell Priming by Modulating Dendritic Cell Function.Semantic proximity Read