Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4.

Journal of endotoxin research - 1 Jan 2003

Ernst Robert K, Hajjar Adeline M, Tsai Jeff H, Moskowitz Samuel M, Wilson Christopher B, Miller Samuel I

Abstract excerpt

Lipid A is the pro-inflammatory component of bacterial lipopolysaccharide, the major surface component of Gram-negative bacteria. Gram-negative bacteria alter the structure of lipid A in response to specific environmental conditions including those found upon colonization of a host. The opportunistic pathogen Pseudomonas aeruginosa synthesizes a unique hexa-acylated lipid A containing palmitate and aminoarabinose...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lipid A
Share to Lipopolysaccharides

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mass Spectrometry

Share to Molecular Weight

Share to Pseudomonas aeruginosa

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Share to Toll-Like Receptor 4

Share to Toll-Like Receptors

Source

Identifiers

PMID: 14733728
DOI: 10.1179/096805103225002764

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4.PMID 14733728Read ↗

Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4Semantic proximity Read ↗

Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa.Semantic proximity Read ↗

A divergent Pseudomonas aeruginosa palmitoyltransferase essential for cystic fibrosis-specific lipid A.Semantic proximity Read ↗

Pseudomonas aeruginosa Exploits Lipid A and Muropeptides Modification as a Strategy to Lower Innate Immunity during Cystic Fibrosis Lung InfectionSemantic proximity Read ↗

Structural Relationship of the Lipid A Acyl Groups to Activation of Murine Toll-Like Receptor 4 by Lipopolysaccharides from Pathogenic Strains of Burkholderia mallei, Acinetobacter baumannii, and Pseudomonas aeruginosaSemantic proximity Read ↗

A <i>Pseudomonas aeruginosa</i> hepta-acylated lipid A variant associated with cystic fibrosis selectively activates human neutrophilsSemantic proximity Read ↗

Role of CFTR, Pseudomonas aeruginosa and Toll-like receptors in cystic fibrosis lung inflammationSemantic proximity Read ↗

Engineering low-endotoxin lipid A in a double auxotroph Pseudomonas aeruginosa to develop safer whole-cell vaccines.Semantic proximity Read ↗

Distinct biological activity of lipopolysaccharides with different lipid A acylation status from mutant strains of Yersinia pestis and some members of genus Psychrobacter.Semantic proximity Read ↗

Human TLR4 and noncanonical inflammasome differ in their ability to respond to distinct lipid A variantsSemantic proximity Read ↗

Mucoid Pseudomonas aeruginosa caused by mucA mutations result in activation of TLR2 in addition to TLR5 in airway epithelial cells.Semantic proximity Read ↗

Microbial Lipid A Remodeling Controls Cross-Presentation Efficiency and CD8 T Cell Priming by Modulating Dendritic Cell Function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.