Article

Early-life gut microbiome and stress-axis perturbations dysregulate systemic, mucosal, and brain immunity

2025-03-20

Abstract excerpt

<h4>Background</h4> Early-life disruptions to the gut microbiome and stress-axis significantly influence the development of immune, neuroendocrine, and other physiological systems. However, the precise microbial species and pathways mediating these effects remain poorly characterized. Using a murine model, we investigated the individual and combined effects of early-life antibiotic exposure and chronic stress on...

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Literature Corpus work: f4f65049-e5ff-5188-b40b-ecdd4faddcd9
DOI: 10.1101/2025.03.19.644259

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