Article

Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes

2021-10-26

Abstract excerpt

Psychological stress alters the gut microbiota and predisposes individuals to increased risk for enteric infections and chronic bowel conditions. Intestinal epithelial cells (IECs) are responsible for maintaining homeostatic interactions between the gut microbiota and its host. In this study, we hypothesized that disruption to colonic IECs is a key factor underlying stress-induced disturbances to intestinal homeos...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 25012bab-5a79-5f89-bad4-3db8d0ea18f9
DOI: 10.1101/2021.10.25.465765

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processesDOI 10.1101/2021.10.25.465765Read

Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processesSemantic proximity Read

Social stress worsens colitis through β-adrenergic–driven oxidative stress in intestinal mucosal compartmentsSemantic proximity Read

Chronic Psychological Stress Disrupted the Composition of the Murine Colonic Microbiota and Accelerated a Murine Model of Inflammatory Bowel DiseaseSemantic proximity Read

Stress-activated brain-gut circuits disrupt intestinal barrier integrity and social behaviourSemantic proximity Read

The structures of the colonic mucosa-associated and luminal microbial communities are distinct and differentially affected by a prolonged murine stressorSemantic proximity Read

Regulation of the stress response by the gut microbiota: Implications for psychoneuroendocrinologySemantic proximity Read

Prenatal Maternal Stress Exacerbates Experimental Colitis of Offspring in AdulthoodSemantic proximity Read

Chronic stress exposure alters the gut barrier: sex-specific effects on microbiota and jejunum tight junctionsSemantic proximity Read

Stress and the gut microbiota-brain axisSemantic proximity Read

Structural and functional alterations in the colonic microbiome of the rat in a model of stress induced irritable bowel syndromeSemantic proximity Read

Role of probiotics in correcting abnormalities of colonic flora induced by stress: Figure 1Semantic proximity Read

Social stress causes gut dysbiosis in male, female, and aggressor miceSemantic proximity Read