Article

The gut–brain axis in irritable bowel syndrome: neuroendocrine and epigenetic pathways

2025-06-03

Abstract excerpt

Irritable bowel syndrome (IBS) is a complex disorder arising from gut–brain axis (GBA) dysfunction, where psychological distress, immune dysregulation, and gut microbiota imbalances interact to shape symptom development. Neurotransmitters and hormones play pivotal roles in mediating visceral sensitivity, gut motility, and emotional processing, linking IBS to neuropsychiatric conditions. Chronic hypothalamic–pituit...

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Literature Corpus work: fca62e36-2295-5e76-869c-b1108732ffee
DOI: 10.20935/acadbiol7748

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