Article

Chronic stress exposure alters the gut barrier: sex-specific effects on microbiota and jejunum tight junctions

2022-09-16

Abstract excerpt

Major depressive disorder (MDD) is the leading cause of disability worldwide. However, 30-50% of patients are unresponsive to commonly prescribed antidepressants, highlighting untapped causal biological mechanisms. Dysfunction in the microbiota-gut-brain axis, the bidirectional communications between the central nervous system and gastrointestinal tract that are modulated by gut microorganisms, has been implicated...

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Identifiers and source

Literature Corpus work: 9231d3bb-afb7-5797-8b61-0b9871035fb0
DOI: 10.1101/2022.09.13.507821

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