Article

Lineage-specific oncogenes drive growth of major forms of human cancer using common downstream mechanisms

2022-09-28

Abstract excerpt

<h4>ABSTRACT</h4> Mutations in hundreds of genes have been associated with formation of human cancer, with different oncogenic lesions prevalent in different cancer types. Yet, the malignant phenotype is simple, characterized by unrestricted growth of cells that invade neighboring healthy tissue and in many cases metastasize to distant organs. One possible hypothesis explaining this dichotomy is that the cancer g...

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Literature Corpus work: 6e22e12f-008b-5907-bbc9-88aec85dd80f
DOI: 10.1101/2022.09.27.509636

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