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Article

Mechanisms of oncogenic cooperation in cancer initiation and metastasis.

The Yale journal of biology and medicine - 1 Dec 2006

Pedraza-Fariña Laura G

Abstract excerpt

Cancer is a disease of extreme heterogeneity. Microarray analysis has identified thousands of genes that are transcriptionally up- or down-regulated in tumor samples; molecularly characterized lesions that play a causative role in tumorigenesis constitute more than 1 percent of the human genome. Such a large number of "cancer genes" stirs the debate of whether it is relevant to continue classifying cancer as a...

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PMID: 17940619
PMCID: PMC1994802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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