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VStrains: De Novo Reconstruction of Viral Strains via Iterative Path Extraction From Assembly Graphs

2022-10-21

Abstract excerpt

With the high mutation rate in viruses, a mixture of closely related viral strains (called viral quasispecies) often co-infect an individual host. Reconstructing individual strains from viral quasispecies is a key step to characterizing the viral population, revealing strain-level genetic variability, and providing insights into biomedical and clinical studies. Reference-based approaches of reconstructing viral st...

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Literature Corpus work
6e0c6fc9-3f30-54d0-95e9-8b756695237d
DOI
10.1101/2022.10.21.513181
Open publication

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VStrains: De Novo Reconstruction of Viral Strains via Iterative Path Extraction From Assembly GraphsDOI 10.1101/2022.10.21.513181
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