Article
De novo assembly of viral quasispecies using overlap graphs
2016-10-12
Abstract excerpt
A viral quasispecies, the ensemble of viral strains populating an infected person, can be highly diverse. For optimal assessment of virulence, pathogenesis and therapy selection, determining the haplotypes of the individual strains can play a key role. As many viruses are subject to high mutation and recombination rates, high-quality reference genomes are often not available at the time of a new disease outbreak....
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 3e398d94-c85e-530c-b068-2855053af4ca
- DOI
- 10.1101/080341