Article

Immune organization defines adaptive immune competence and clinical outcome in breast cancer

2026-07-20

Abstract excerpt

<h4>Summary</h4> Tumor-infiltrating lymphocytes (TILs) are widely used to assess antitumor immunity in breast cancer but may not reflect the functional competence of adaptive immune responses. We show that immune organization, reflected by tertiary lymphoid structures (TLS) and coordinated humoral and cellular immune programs, represents a distinct dimension of tumor immunity beyond lymphocyte abundance. By integ...

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Literature Corpus work: 6df826d4-79b3-528b-8bd1-8eee2c23f14d
DOI: 10.64898/2026.07.17.26358324

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