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Article

AGGRESCAN: method, application, and perspectives for drug design.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

de Groot Natalia S, Castillo Virginia, Graña-Montes Ricardo, Ventura Salvador

Abstract excerpt

Protein aggregation underlies the development of an increasing number of conformational human diseases of growing incidence, such as Alzheimer's and Parkinson's diseases. Furthermore, the accumulation of recombinant proteins as intracellular aggregates represents a critical obstacle for the biotechnological production of polypeptides. Also, ordered protein aggregates constitute novel and versatile...

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PMID: 22183539
DOI: 10.1007/978-1-61779-465-0_14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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