Article

Improving AlphaFold2-based Protein Tertiary Structure Prediction with MULTICOM in CASP15

2023-05-01

Abstract excerpt

Since CASP14, AlphaFold2 has become the standard method for protein tertiary structure prediction. One remaining challenge in the field is to further improve the accuracy of AlphaFold2-based protein structure prediction. To address this challenge, we developed a new version of the MULTICOM system to sample diverse multiple sequence alignments (MSAs) and structural templates to improve the input for AlphaFold2 to g...

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Literature Corpus work: 7078eb6d-b15e-5a0b-87b9-d2e37c75be3d
DOI: 10.1101/2023.05.01.538929

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