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Article

Acceleration and suppression of resistance development by antibiotic combinations.

BMC genomics - 26 Apr 2017

Suzuki Shingo, Horinouchi Takaaki, Furusawa Chikara

Abstract excerpt

BACKGROUND: The emergence and spread of antibiotic resistance in bacteria is becoming a global public health problem. Combination therapy, i.e., the simultaneous use of multiple antibiotics, is used for long-term treatment to suppress the emergence of resistant strains. However, the effect of the combinatorial use of multiple drugs on the development of resistance remains elusive, especially in a quantitative...

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Identifiers

PMID: 28446153
DOI: 10.1186/s12864-017-3718-2
PMCID: PMC5405530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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