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Article

Mutation and evolution of antibiotic resistance: antibiotics as promoters of antibiotic resistance?

Current drug targets - 1 Aug 2002

Blázquez Jesus, Oliver Antonio, Gómez-Gómez José-María

Abstract excerpt

Antibiotic resistance appearance and spread have been classically considered the result of a process of natural selection, directed by the use of antibiotics. Bacteria, that have to face the antibiotic challenge, evolve to acquire resistance and, under this strong selective pressure, only the fittest survive, leading to the spread of resistance mechanisms and resistant clones. Horizontal transference of...

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Identifiers

PMID: 12102604
DOI: 10.2174/1389450023347579

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Source receipt: pubmed, retrieved 7 Sept 2026.

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