Article

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

2016-05-03

Abstract excerpt

<h4>Motivation</h4> LD score regression is a reliable and efficient method of using genome-wide association study (GWAS) summary-level results data to estimate the SNP heritability of complex traits and diseases, partition this heritability into functional categories, and estimate the genetic correlation between different phenotypes. Because the method relies on summary level results data, LD score regression is...

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Literature Corpus work: 6d639db0-c051-5b81-ac2b-46c71c16cb9c
DOI: 10.1101/051094

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