Article

Pleiotropic effects of BAFF on the senescence-associated secretome and growth arrest

2022-10-27

Abstract excerpt

Senescent cells release a variety of cytokines, proteases, and growth factors collectively known as the senescence-associated secretory phenotype (SASP). Sustained SASP contributes to a pattern of chronic inflammation associated with aging and implicated in many age-related diseases. Here, we investigated the expression and function of the immunomodulatory cytokine BAFF (B-cell activating factor), a SASP protein,...

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Literature Corpus work: 6d3b1498-90ef-57d7-b97c-4bf6c86d9c11
DOI: 10.1101/2022.10.25.513730

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