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Sex-Dependent Association of DNA Methylation in the Coding Region of the Corticotropin-Releasing Hormone Gene and Schizophrenia

2021-03-11

Abstract excerpt

<title>Abstract</title> <p>Schizophrenia (SCZ) is a common mental disease causing severe chronic disability. Epigenetic changes in HPA axis-related genes are considered to play an important role in SCZ pathogenesis. Unfortunately, the methylation status of the corticotropin-releasing hormone ( CRH ) gene, which is the central driving force in the HPA axis, has not been reported in SCZ patients. Here, we used the...

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Literature Corpus work
6d38d95e-98b9-500d-b470-eb6a2bcec0a8
DOI
10.21203/rs.3.rs-277493/v1
Open publication

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Sex-Dependent Association of DNA&nbsp;Methylation in&nbsp;the Coding Region&nbsp;of the Corticotropin-Releasing Hormone&nbsp;Gene and SchizophreniaDOI 10.21203/rs.3.rs-277493/v1
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