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Article

Catechol-O-methyltransferase gene promoter methylation as a peripheral biomarker in male schizophrenia.

European psychiatry : the journal of the Association of European Psychiatrists - 1 Jul 2017

Gao S, Cheng J, Li G, Sun T, Xu Y, Wang Y, Du X, Xu G, Duan S

Abstract excerpt

As an epigenetic modification, DNA methylation may reflect the interaction between genetic and environmental factors in the development of schizophrenia (SCZ). Catechol-O-methyltransferase (COMT) gene is a promising candidate gene of SCZ. In the present study, we investigate the association of COMT methylation with the risk of SCZ using bisulfite pyrosequencing technology. Significant association between DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28545007
DOI: 10.1016/j.eurpsy.2017.03.002

Genes

COMT

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