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Article

Increased DNA methylation status of the serotonin receptor 5HTR1A gene promoter in schizophrenia and bipolar disorder.

Journal of affective disorders - 1 Aug 2011

Carrard Anthony, Salzmann Annick, Malafosse Alain, Karege Félicien

Abstract excerpt

BACKGROUND: Epigenetic changes may play a role in the etiology of psychotic diseases. It has been demonstrated that the serotonin receptor, 5HTR1A, is implicated in schizophrenia (SCZ) and bipolar disorder (BPD). The aim of this study was to investigate the methylation status of a promoter region of the 5HTR1A gene in BPD and SCZ patients. METHODS: Our study included 58 BPD and 40 SCZ (DSM-IV criteria) as well as...

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Identifiers

PMID: 21453976
DOI: 10.1016/j.jad.2011.03.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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