Article
Lung cancer pathogenesis and poor response to therapy were dependent on driver oncogenic mutations.
Life sciences - 15 Jan 2021
Sun Xin, Li Kai, Zhao Rui, Sun Ye, Xu Jie, Peng Zi-Yang, Song Run-Dong, Ren Hong, Tang Shou-Ching
Abstract excerpt
AIMS: Lung cancer was the most fatal malignancy, dominated the cancer related mortality list for years, and we tried to distinguish the lung adenocarcinoma patients at higher risk from those bearing lower therapy resistance and recurrence risk. MATERIALS: Patients information from clinical Sequencing Cohorts and from the Regional Medical Center of the Middle-West China were included. The whole-exome sequencing...
Topics
- Adenocarcinoma of Lung
- Aged
- Biomarkers, Tumor
- Carcinogenesis
- Female
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Mutation
- Oncogenes
- Smoking
- Survival Rate
- Treatment Outcome
