Article
Large-scale clinico-genomic profile of non-small cell lung cancer with KRAS G12C: Results from LC-SCRUM-Asia study.
Lung cancer (Amsterdam, Netherlands) - 1 Feb 2023
Tamiya Yutaro, Matsumoto Shingo, Zenke Yoshitaka, Yoh Kiyotaka, Ikeda Takaya, Shibata Yuji, Kato Terufumi, Nishino Kazumi, Nakamura Atsushi, Furuya Naoki, Miyamoto Shingo, Kuyama Shoichi, Nomura Shogo, Ikeno Takashi, Udagawa Hibiki, Sugiyama Eri, Nosaki Kaname, Izumi Hiroki, Sakai Tetsuya, Hashimoto Naozumi, Goto Koichi
Abstract excerpt
INTRODUCTION: KRAS G12C is an oncogenic driver mutation, accounting for approximately 14% of Caucasian patients with non-small cell lung cancer (NSCLC). Recently, several KRAS G12C-targeted drugs have been developed; however, the clinico-genomic characteristics of NSCLC patients with KRAS G12C remain unclear. MATERIALS AND METHODS: Based on the large-scale prospective lung cancer genomic screening project...
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