Smoking and risk of colorectal cancer according to KRAS and BRAF mutation status in a Japanese prospective Study.

doi:10.1093/carcin/bgad046

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Article

Smoking and risk of colorectal cancer according to KRAS and BRAF mutation status in a Japanese prospective Study.

Carcinogenesis - 18 Aug 2023

Nakano Shiori, Yamaji Taiki, Shiraishi Kouya, Hidaka Akihisa, Shimazu Taichi, Kuchiba Aya, Saito Masahiro, Kunishima Fumihito, Nakaza Ryouji, Kohno Takashi, Sawada Norie, Inoue Manami, Tsugane Shoichiro, Iwasaki Motoki

Abstract excerpt

Although smoking is a major modifiable risk factor for many types of cancer, evidence for colorectal cancer is equivocal in Asian populations. Recent Western studies have proposed that the association between smoking and colorectal cancer is restricted to specific tumor molecular subtypes. Howeve...

Topics

Humans
Cohort Studies
Colorectal Neoplasms
East Asian People
Mutation
Prospective Studies
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins p21(ras)
Smoking

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Identifiers

PMID: 37352389
DOI: 10.1093/carcin/bgad046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-37352389-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.