Article

BMI-related Genetic Factors and COPD Imaging Phenotypes

2024-08-20

Abstract excerpt

<h4>Background</h4> While low body mass index (BMI) is associated with emphysema and obesity is associated with airway disease in chronic obstructive pulmonary disease (COPD), the underlying mechanisms are unclear. <h4>Methods</h4> We aggregated genetic variants from population-based genome-wide association studies to generate a polygenic score of BMI (PGS BMI ). We calculated this score for participants from COPD...

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Literature Corpus work: 6cf3f246-7de5-568c-85c9-9601ce67c446
DOI: 10.1101/2024.08.16.24312135

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