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Article

Body Mass Index-related genetic factors and COPD imaging phenotypes.

Annals of the American Thoracic Society - 1 May 2026

Zhang Jingzhou, Moll Matthew, Debban Catherine L, Hobbs Brian D, Rijhwani Heena, Washko George R, Celli Bartolome R, Silverman Edwin K, Bakke Per, Oelsner Elizabeth C, Barr R Graham, Agustí Alvar, Faner Rosa, Bruselle Guy G, Humphries Stephen M, Lynch David A, Dupuis Josée, Manichaikul Ani W, O'Connor George T, Cho Michael H

Abstract excerpt

RATIONALE: While low body mass index (BMI) is associated with emphysema and obesity is associated with airway disease in chronic obstructive pulmonary disease (COPD), the underlying mechanisms are unclear. OBJECTIVES: To examine the association between BMI-related genetic variants and emphysema and airway disease imaging phenotypes. METHODS: We aggregated genetic variants from population-based genome-wide...

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Share to Pulmonary Emphysema
Share to Pulmonary Disease, Chronic Obstructive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Genetic Risk Score

Share to Genome-Wide Association Study

Share to Obesity

Share to Tomography, X-Ray Computed

Source

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Identifiers

PMID: 41721747
DOI: 10.1093/annalsats/aaoag007
PMCID: PMC13152661

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